The Most Frequent Neurodegenerative Movement Disorder...

2 Introduction 2.1 Overview The most frequent neurodegenerative movement disorder today is Parkinson Disease (Barth et al., 2011), with a prevalence which increases with age – from 0.01% of people in the age group 40 to 44 years, increasing steadily to approximately 1% at age 65 and 22% at age 85 or over. Due to an aging society, increasing industrialization and environmental factors, the number of patients will grow rapidly in the forthcoming decades. Parkinson’s disease (PD) is a progressive disorder of unknown etiology that has no cure. It is characterized by bradykinesia, rest tremor, cogwheel rigidity and postural instability, along with a number of non-motor signs. The neurochemical hallmark of PD is dopamine loss in the nigrostriatal dopamine system (Adler, 2011). In the substantia nigra (SN) of people with PD there is a loss of neuronal cells, demonstrated by the degeneration of brainstem nuclei (Brooks, 1998). This typically shows as Lewy bodies – spherical masses of protein that develop inside nerve cells. However the progression of neuronal loss is quite variable in different PD patients and at different phases of the disease. At present there is no treatment that affects the degeneration, for example by slowing the rate of cell death or by protecting neurons. Unfortunately by the time that PD is first diagnosed, 60% to 70% of the neurons in the SN responsible for dopamine have degenerated and the striatal dopamine content is reduced by 80% (Adler, 2011) andShow MoreRelatedParkinson Disease : A Progressive Disorder4669 Words   |  19 PagesOverview The most frequent neurodegenerative movement disorder today is Parkinson Disease (Barth et al., 2011), with a prevalence which increases with age – from 0.01% of people in the age group 40 to 44 years, increasing steadily to approximately 1% at age 65 and 22% at age 85 or over. Due to an aging society, increasing industrialization and environmental factors, the number of patients will grow rapidly in the forthcoming decades. Parkinson’s disease (PD) is a progressive disorder of unknown etiologyRead MoreChronic Conditions That Can Not Be Cured1878 Words   |  8 PagesLTC’s has been implemented due to the increase in the ageing population which in turn produces an increase in the incidence of LTC’s such as diabetes, Parkinson Disease [PD], pernicious anaemia, chronic obstructive pulmonary disease, neurological and heart conditions. Due to word restriction the author will discuss diabetes and Parkinson’s disease. Diabetes is a lifelong condition that causes a person’s blood sugar to become too high or too low as the pancreas no longer produces the right amount

The Industrial Advances Of Europe During The Nineteenth...

At the start of the twentieth century, Europe was emerged in a crisis. Britain and France were almost at war and tensions between the Western nations were rising (Civilizations 541). Despite these negativities, Europe was advancing in new technologies making manufacturing goods easier and more efficient. Along with technological and industrial advances came wars, movements, and idealism. Europe suffered greatly between 1870-1920, but also made revolutionary advances. Following this further, some industrial advances that occurred took place in the steel, electricity, and chemical industries. Before the steel industry boom, to make steel people used the cementation process. The cementation process took days and was expensive. Henry Bessemer created an efficient and more effective way to produce steel with his invented of the Bessemer Process. In the 1880 s electricity was made available for commercial and domestic use (Civilizations 548). Electricity powered different ways of transport ation and helped to produce new chemical advances. The chemical advances helped in more ways than one. It produced textiles and soap since more people were concerned with their hygiene. In addition to the industrial advances came technological advances. Nikolaus August Otto invented the first practical four-stroke internal combustion engine in 1876. He called it the Otto Cycle Engine and proceeded to put it into a motorcycle (Bellis). To compete with the combustion engine, Rudolf DieselShow MoreRelated The European Expansion and its Effects on the World Essay1260 Words   |  6 Pagestechnological advances, which in turn stimulated, and were stimulated by science.† (p. 403) The European scientific revolution was fueled by the blending of â€Å"liberal† and â€Å"servile† arts, in other words, science and technology. Because of the European expansion taking place throughout the world, new commerce and industries were advancing, creating the need for new technolog y and science. The theories and inventions that Copernicus, Galileo, and Newton provided were the fist major advances during the scientificRead MoreThe Industrial Revolutions Influence on European Society1389 Words   |  6 PagesIn the late nineteenth and early twentieth centuries the Industrial Revolution in Europe had a significant influence on society. There were many changes in social classes and equality. The rise of the middle class had a momentous effect on the population of Europe and was a catalyst for many changes in the social makeup of the region. The influence of technology and electricity changed many aspects of social interaction and created a new class system. The migration of workers and the separation ofRead MoreThe Decline Of Slavery During The Nineteenth Century962 Words   |  4 PagesFor roughly two centuries, millions of Africans were transported against their will to the New World to work in excruciating labor and withstand harsh conditions. Inhuman Traffi ck exceeds at indicating the revolutionary effects that would follow the end of slave trade on European countries. In order to understand this concept, it is crucial to note the changes European society went through during the abolitionist movements and the ending of slavery. Industrialization also attributes to the many ofRead MoreChanges Europe Experienced During The Industrial Revolution1620 Words   |  7 PagesChanges Europe experienced during the Industrial Revolution o The Industrial Revolution of the late eighteenth and middle nineteenth was progressive on the grounds that it modified, revolutionized the productive capacity of England, Europe and United States. In any case, the upheaval was something more than just new machines, smoke-burping processing plants, expanded efficiency and an expanded way of life. It was an upheaval which changed English, European, and American culture down to its extremelyRead MoreAdvantages And Disadvantages Of The Gilded Age1035 Words   |  5 Pagesend of the nineteenth century to the middle of the twentieth century many economic changes occurred, from booms to busts, but all effected minorities less favorably. At the end of the nineteenth century began an era of industrialization that created an economic upturn called the gilded age. Hallmarks of this age were technological advances, banking innovations, and wealth concentrations. Railroad construction, advances in steel production, and electrical innovation drove industrial and economicRead MoreMinstrel Shows and Theater856 Words   |  3 PagesThe 19th century was a time period full of disagreements and wishful thinking. During this time, African Americans were trying to become free from slavery. This led to a Civil War. The 1800’s were a hard time for African Americans, after the Civil War many expressed their thoughts and feelings through plays like Minstrel Shows and other forms of theatre. During this time period, America was in the middle of its Industrial Revolution. It was the beginning of the growth of the infrastructure forRead MoreThe Great Divergence : China, Europe And The Making Of The Modern World Economy Essay1726 Words   |  7 PagesDuring the long time of economic history, the Industrial Revolution happened in England in the eighteenth century is definitely a turning point which triggers many scholars’ interests. Gregory Clark, the author of A Farewell to Alms: A Brief Economic History of the World, claims that the average person of 1800 was no better off than their remote ancestors of the Palaeolithic according to the Malthusian Trap. Then he focuses on solving three questions: Why did the Malthusian Trap persist so longRead MoreThe Rise Of The Industrial Revolution1464 Words   |  6 Pagesâ€Å"If I had asked people what they wanted, they would have said faster horses,† said Henry Ford. The Industrial Revolution was a stage in the evolution of human society in which a lot of change was effected, not only because of all the new technology being invented, but in the structure of society. As people started to stand up for their rights and rejecting the long-standing institution of wealth determining status, the Old Regime had to adapt. France’s Constitution of 1791 had one law that classifiedRead MoreHow Did the Indsutrial Development Unite or Divide the North and the South?143 4 Words   |  6 PagesDuring the Civil War, the advances of the Industrial Revolution introduced great changes in the industrial and technological development. Both the North and the South created many advances in railroad and water transportation. The Union, however, was far more advanced technologically than the Confederate states . Consequently, the North made greater and more effective use of progress in weapons, communication, transportation and medicine than South . Although the industrial development made the nationRead MoreImperialism in the 19th century1746 Words   |  7 PagesThere was a great deal of Imperialism in the 19th century, led by mostly westerners from Europe. Imperialism is the act in which one nation extends its rule over another. Imperialism had a substantial effect on the 19th century throughout the entire world by bringing upon changes to many different countries, for better and for worse, especially to Africa. Prior to the nineteenth century, westerners did interfere with many of the affairs of nations outside of their boarders, so signs of imperialism

Deception Point Page 21 Free Essays

Tolland groaned. â€Å"Now he’s showing off. What Corky means is that we can prove a rock is a meteorite simply by measuring its chemical content. We will write a custom essay sample on Deception Point Page 21 or any similar topic only for you Order Now † â€Å"Hey, ocean boy!† Corky chided. â€Å"Let’s leave the science to the scientists, shall we?† He immediately turned back to Rachel. â€Å"In earth rocks, the mineral nickel occurs in either extremely high percentages or extremely low; nothing in the middle. In meteorites, though, the nickel content falls within a midrange set of values. Therefore, if we analyze a sample and find the nickel content reflects a midrange value, we can guarantee beyond the shadow of a doubt that the sample is a meteorite.† Rachel felt exasperated. â€Å"Okay, gentlemen, fusion crusts, chondrules, midrange nickel contents, all of which prove it’s from space. I get the picture.† She laid the sample back on Corky’s table. â€Å"But why am I here?† Corky heaved a portentous sigh. â€Å"You want to see a sample of the meteorite NASA found in the ice underneath us?† Before I die here, please. This time Corky reached in his breast pocket and produced a small, disk-shaped piece of stone. The slice of rock was shaped like an audio CD, about half an inch thick, and appeared to be similar in composition to the stony meteorite she had just seen. â€Å"This is a slice of a core sample that we drilled yesterday.† Corky handed the disk to Rachel. The appearance certainly was not earth-shattering. It was an orangish-white, heavy rock. Part of the rim was charred and black, apparently a segment of the meteorite’s outer skin. â€Å"I see the fusion crust,† she said. Corky nodded. â€Å"Yeah, this sample was taken from near the outside of the meteorite, so it still has some crust on it.† Rachel tilted the disk in the light and spotted the tiny metallic globules. â€Å"And I see the chondrules.† â€Å"Good,† Corky said, his voice tense with excitement. â€Å"And I can tell you from having run this thing through a petrographic polarizing microscope that its nickel content is midrange-nothing like a terrestrial rock. Congratulations, you’ve now successfully confirmed the rock in your hand came from space.† Rachel looked up, confused. â€Å"Dr. Marlinson, it’s a meteorite. It’s supposed to come from space. Am I missing something here?† Corky and Tolland exchanged knowing looks. Tolland put a hand on Rachel’s shoulder and whispered, â€Å"Flip it over.† Rachel turned the disk over so she could see the other side. It took only an instant for her brain to process what she was looking at. Then the truth hit her like a truck. Impossible! she gasped, and yet as she stared at the rock she realized her definition of â€Å"impossible† had just changed forever. Embedded in the stone was a form that in an earth specimen might be considered commonplace, and yet in a meteorite was utterly inconceivable. â€Å"It’s†¦ † Rachel stammered, almost unable to speak the word. â€Å"It’s†¦ a bug! This meteorite contains the fossil of a bug!† Both Tolland and Corky were beaming. â€Å"Welcome aboard,† Corky said. The torrent of emotions that gripped Rachel left her momentarily mute, and yet even in her bewilderment, she could clearly see that this fossil, beyond question, had once been a living biological organism. The petrified impression was about three inches long and looked to be the underside of some kind of huge beetle or crawling insect. Seven pairs of hinged legs were clustered beneath a protective outer shell, which seemed to be segmented in plates like that of an armadillo. Rachel felt dizzy. â€Å"An insect from space†¦ â€Å" â€Å"It’s an isopod,† Corky said. â€Å"Insects have three pairs of legs, not seven.† Rachel did not even hear him. Her head was spinning as she studied the fossil before her. â€Å"You can clearly see,† Corky said, â€Å"that the dorsal shell is segmented in plates like a terrestrial pill bug, and yet the two prominent tail-like appendages differentiate it as something closer to a louse.† Rachel’s mind had already tuned Corky out. The classification of the species was totally irrelevant. The puzzle pieces now came crashing into place-the President’s secrecy, the NASA excitement†¦ There is a fossil in this meteorite! Not just a speck of bacteria or microbes, but an advanced life-form! Proof of life elsewhere in the universe! 23 Ten minutes into the CNN debate, Senator Sexton wondered how he could have been worried at all. Marjorie Tench was grossly overestimated as an opponent. Despite the senior adviser’s reputation for ruthless sagacity, she was turning out to be more of a sacrificial lamb than a worthy opponent. Granted, early in the conversation Tench had grabbed the upper hand by hammering the senator’s prolife platform as biased against women, but then, just as it seemed Tench was tightening her grip, she’d made a careless mistake. While questioning how the senator expected to fund educational improvements without raising taxes, Tench made a snide allusion to Sexton’s constant scapegoating of NASA. Although NASA was a topic Sexton definitely intended to address toward the end of the discussion, Marjorie Tench had opened the door early. Idiot! â€Å"Speaking of NASA,† Sexton segued casually. â€Å"Can you comment on the rumors I keep hearing that NASA has suffered another recent failure?† Marjorie Tench did not flinch. â€Å"I’m afraid I have not heard that rumor.† Her cigarette voice was like sandpaper. â€Å"So, no comment?† â€Å"I’m afraid not.† Sexton gloated. In the world of media sound bites, â€Å"no comment† translated loosely to â€Å"guilty as charged.† â€Å"I see,† Sexton said. â€Å"And how about the rumors of a secret, emergency meeting between the President and the administrator of NASA?† This time Tench looked surprised. â€Å"I’m not sure what meeting you’re referring to. The President takes many meetings.† â€Å"Of course, he does.† Sexton decided to go straight at her. â€Å"Ms. Tench, you are a great supporter of the space agency, is that right?† Tench sighed, sounding tired of Sexton’s pet issue. â€Å"I believe in the importance of preserving America’s technological edge-be that military, industry, intelligence, telecommunications. NASA is certainly part of that vision. Yes.† In the production booth, Sexton could see Gabrielle’s eyes telling him to back off, but Sexton could taste blood. â€Å"I’m curious, ma’am, is it your influence behind the President’s continued support of this obviously ailing agency?† Tench shook her head. â€Å"No. The President is also a staunch believer in NASA. He makes his own decisions.† Sexton could not believe his ears. He had just given Marjorie Tench a chance to partially exonerate the President by personally accepting some of the blame for NASA funding. Instead, Tench had thrown it right back at the President. The President makes his own decisions. It seemed Tench was already trying to distance herself from a campaign in trouble. No big surprise. After all, when the dust settled, Marjorie Tench would be looking for a job. Over the next few minutes, Sexton and Tench parried. Tench made some weak attempts to change the subject, while Sexton kept pressing her on the NASA budget. â€Å"Senator,† Tench argued, â€Å"you want to cut NASA’s budget, but do you have any idea how many high-tech jobs will be lost?† Sexton almost laughed in the woman’s face. This gal is considered the smartest mind in Washington? Tench obviously had something to learn about the demographics of this country. High-tech jobs were inconsequential in comparison to the huge numbers of hardworking blue-collar Americans. Sexton pounced. â€Å"We’re talking about billions in savings here, Marjorie, and if the result is that a bunch of NASA scientists have to get in their BMWs and take their marketable skills elsewhere, then so be it. I’m committed to being tough on spending.† How to cite Deception Point Page 21, Essay examples

Does it or Does it Not Essay Example For Students

Does it or Does it Not? Essay To be able to believe that some one or thing exists, it must be a universal idea that others have at least heard of. It also must be tangible to a human being and have some sort of physical evidence or others accounts of evidence to show that it does in fact exist. If the object or person cannot provide hard physical evidence, then how does it get humans such as our selves to believe in them? The answer seems simple enough, faith. Religion, in general, has been around since human beings have first graced this planet. No one knows exactly how it actually came about, but we know that it is here and still is here today. God may or may not exist. Through the faith of the people He most definitely exists to them.He is praised, worshiped, and glorified by over one billion people through out the world. Those one billion people trust and believe that God exists without having to have physical or logical evidence. They say that through all things God exists. Why? Because supposedly He created all living things on this planet. Scientists, however, have their own idea of how Earth was created. So, how do we know that He truly does exist? We cannot see what He looks like, or what He sounds like. We also do not have records of His birth or death. There are many beautiful murals and paintings of Him through out the world, but which one is He? How can someone devote their selves and time into something they cannot see or hear? It seems like a waste of time to some. To others, religion acts as a crutch for comfort and safety. Some say that he does exist in our everyday lives in everything that we experience. Others, however, believe that He exists in money and say that if people donate money the Good Lord will heal you and love you, but you have to donate some money first before he can do anything. It is sketchy and since when was having faith in God a paid service? Some people only pray for what they need, and sometimes might not even really need it and act as if God is Santa Claus. He is also a crutch for those who are insecure and need to find comfort. Therefore, meaning tha t it could be a trick of the mind. Which also demonstrates why He appears in visions and dreams to some people. The only real evidence that we have of God is through the bible. The bible is supposedly based on the first and second hand accounts of the apostles and his followers. Through out the bible it displays the many miracles performed by God, stories teach parables and morals, and most of all the Old Testament shows a great amount of faith in Him through his chosen leaders and the people. We do know that the apostles and Jesus did in fact exist then through birth certificates, baptismal certificates, or other means of showing that they were part of this world in their own time. Through them, they claimed, God performed his miracles and spread the good news. Our first pope in the church was one of the apostles, and some of the others to follow are descendants of him. That could also be another account of evidence that he did exist. Saying that God does indeed exist is like skating on thin ice, because it is too risky to go out there and just think everything is going to be ok without knowi ng for sure if it really will be. However, many people still believe that God does truly exist in their heart, mind, body, and soul. Also, that He does in fact perform miracles and helps those who are in need of it.In conclusion, to believe in something it should have physical and logical evidence that it indeed does exist, tangibly. If it cannot bring evidence that it does exist tangibly, does it really exist? If so, then how? Which brings Gods existence back to question. It is very hard to place a definite answer to this question. God may exist, no one